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Article

Novel sib pair selection strategy increases power in quantitative association analysis.

Behavior genetics - 1 Sept 2009

Kwan Johnny S H, Cherny Stacey S, Kung Annie W C, Sham Pak C

Abstract excerpt

Quantitative-trait association studies have been widely used in search for genetic loci for complex traits in recent years. Yet, fiscal constraints still prohibit many on-going research projects from recruiting a large number of individuals for genotyping to reach a desired level of statistical power. Accordingly, in this article, we describe a novel sib pair sampling strategy for genotyping in QTL association...

Topics

Algorithms
Alleles
Chromosome Mapping
Computer Simulation
Family Health
Genetic Techniques
Humans
Likelihood Functions
Linkage Disequilibrium
Models, Genetic
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

Selection, Genetic

Siblings

Source

Identifiers

PMID: 19568925
DOI: 10.1007/s10519-009-9284-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19568925-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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