Article
Sib-based detection of QTLs.
Genetic epidemiology - 1 Jan 1995
Suarez B K, Hampe C L, O'Rourke D, Van Eerdewegh P, Reich T
Abstract excerpt
Association and transmission/nontransmission analyses were used in a split sample design to identify disease susceptibility alleles at two loci. Sib-pair analysis on various subsets of the data identified an additional four regions that yielded signals of disease predisposing quantitative trait loci (QTLs). Three of these four regions represented Type I errors. A new simulation indicates that a multiplex sampling...
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