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Article

Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS).

Genetic epidemiology - 1 Jul 2011

Feng Tao, Elston Robert C, Zhu Xiaofeng

Abstract excerpt

It is generally known that risk variants segregate together with a disease within families, but this information has not been used in the existing statistical methods for detecting rare variants. Here we introduce two weighted sum statistics that can apply to either genome-wide association data or resequencing data for identifying rare disease variants: weights calculated based on sibpairs and odd ratios,...

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PMID: 21594893
DOI: 10.1002/gepi.20588
PMCID: PMC3114642

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IFIH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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