Article
Joint analysis of binary and quantitative traits with data sharing and outcome-dependent sampling.
Genetic epidemiology - 1 Apr 2012
Zheng Gang, Wu Colin O, Kwak Minjung, Jiang Wenhua, Joo Jungnam, Lima Joao A C
Abstract excerpt
We study the analysis of a joint association between a genetic marker with both binary (case-control) and quantitative (continuous) traits, where the quantitative trait values are only available for the cases due to data sharing and outcome-dependent sampling. Data sharing becomes common in genetic association studies, and the outcome-dependent sampling is the consequence of data sharing, under which a phenotype...
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