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Article

Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use.

PloS one - 29 Jun 2009

Le Thuy, Chiarella Jennifer, Simen Birgitte B, Hanczaruk Bozena, Egholm Michael, Landry Marie L, Dieckhaus Kevin, Rosen Marc I, Kozal Michael J

Abstract excerpt

BACKGROUND: It is largely unknown how frequently low-abundance HIV drug-resistant variants at levels under limit of detection of conventional genotyping (<20% of quasi-species) are present in antiretroviral-experienced persons experiencing virologic failure. Further, the clinical implications of low-abundance drug-resistant variants at time of virologic failure are unknown. METHODOLOGY/PRINCIPAL FINDINGS: Plasma...

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Identifiers

PMID: 19562031
DOI: 10.1371/journal.pone.0006079
PMCID: PMC2698118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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