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Article

Low-Abundance Drug-Resistant HIV-1 Variants: Finding Significance in an Era of Abundant Diagnostic and Therapeutic Options

11 Feb 2009

Abstract excerpt

(See the article by Simen et al., on pages 693–701.) Several prospective and retrospective studies have shown that genotypic testing for drug-resistant HIV-1 variants has helped health-care providers better un-derstand patient responses to antiretrovi-ral therapy (ART) andmakewiser choices for both initial and salvage therapy. The standard approach to genotypic resis-tance testing begins with plasma HIV-1 RNA...

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PMID: 19210160
DOI: 10.1086/596737

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