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Next-generation sequencing (NGS) reveals low-abundance HIV-1 drug resistance mutations among patients experiencing virological failure at the time of therapy switching in Uganda

2022-08-04

Abstract excerpt

<h4>Background: </h4> The emergence and spread of antiretroviral drug resistant HIV-1 variants is one of the major factors associated with therapeutic failure in persons living with HIV (PLWH) as it jeopardizes the efforts to reduce the progression to AIDS. Whereas Sanger sequencing is the most appropriate conventional method for HIV drug resistance testing, it has limited capacity to detect low-abundance variants...

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Literature Corpus work
a13a6bb6-d149-5d3b-aed2-901e0e090621
DOI
10.12688/f1000research.121980.1
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