Article
Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Iwayama Yoshimi, Hattori Eiji, Maekawa Motoko, Yamada Kazuo, Toyota Tomoko, Ohnishi Tetsuo, Iwata Yasuhide, Tsuchiya Kenji J, Sugihara Genichi, Kikuchi Mitsuru, Hashimoto Kenji, Iyo Masaomi, Inada Toshiya, Kunugi Hiroshi, Ozaki Norio, Iwata Nakao, Nanko Shinichiro, Iwamoto Kazuya, Okazaki Yuji, Kato Tadafumi, Yoshikawa Takeo
Abstract excerpt
Deficits in prepulse inhibition (PPI) are a biological marker for psychiatric illnesses such as schizophrenia and bipolar disorder. To unravel PPI-controlling mechanisms, we previously performed quantitative trait loci (QTL) analysis in mice, and identified Fabp7, that encodes a brain-type fatty acid binding protein (Fabp), as a causative gene. In that study, human FABP7 showed genetic association with...
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