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Article

In silico whole genome association scan for murine prepulse inhibition.

PloS one - 1 Jan 2009

Webb Bradley Todd, McClay Joseph L, Vargas-Irwin Cristina, York Timothy P, van den Oord Edwin J C G

Abstract excerpt

BACKGROUND: The complex trait of prepulse inhibition (PPI) is a sensory gating measure related to schizophrenia and can be measured in mice. Large-scale public repositories of inbred mouse strain genotypes and phenotypes such as PPI can be used to detect Quantitative Trait Loci (QTLs) in silico. However, the method has been criticized for issues including insufficient number of strains, not controlling for false...

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Identifiers

PMID: 19370154
DOI: 10.1371/journal.pone.0005246
PMCID: PMC2666808

Genes

DTNBP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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