Article

Role of an Atypical Cadherin Gene, <i>Cdh23</i> in Prepulse Inhibition and Implication of <i>CDH23</i> in Schizophrenia

2020-10-29

Abstract excerpt

We previously identified quantitative trait loci (QTL) for prepulse inhibition (PPI), an endophenotype of schizophrenia, on mouse chromosome 10 and reported Fabp7 as a candidate gene from an analysis of F2 mice from inbred strains with high (C57BL/6N; B6) and low (C3H/HeN; C3H) PPI levels. Here, we reanalyzed the previously reported QTLs with increased marker density. The highest LOD score (26.66) peaked at a syn...

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Literature Corpus work: 11a0586f-2755-5099-9b1a-62135b9a78dd
DOI: 10.1101/2020.10.29.360180

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