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Article

Transcription factor SP4 is a susceptibility gene for bipolar disorder.

PloS one - 1 Jan 2009

Zhou Xianjin, Tang Wei, Greenwood Tiffany A, Guo Shengzhen, He Lin, Geyer Mark A, Kelsoe John R

Abstract excerpt

The Sp4 transcription factor plays a critical role for both development and function of mouse hippocampus. Reduced expression of the mouse Sp4 gene results in a variety of behavioral abnormalities relevant to human psychiatric disorders. The human SP4 gene is therefore examined for its associatio...

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Identifiers

PMID: 19401786
DOI: 10.1371/journal.pone.0005196
PMCID: PMC2674320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19401786-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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