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Article

Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.

PLoS biology - 1 Nov 2007

Watanabe Akiko, Toyota Tomoko, Owada Yuji, Hayashi Takeshi, Iwayama Yoshimi, Matsumata Miho, Ishitsuka Yuichi, Nakaya Akihiro, Maekawa Motoko, Ohnishi Tetsuo, Arai Ryoichi, Sakurai Katsuyasu, Yamada Kazuo, Kondo Hisatake, Hashimoto Kenji, Osumi Noriko, Yoshikawa Takeo

Abstract excerpt

Deficits in prepulse inhibition (PPI) are a biological marker for schizophrenia. To unravel the mechanisms that control PPI, we performed quantitative trait loci (QTL) analysis on 1,010 F2 mice derived by crossing C57BL/6 (B6) animals that show high PPI with C3H/He (C3) animals that show low PPI. We detected six major loci for PPI, six for the acoustic startle response, and four for latency to response peak, some...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Acid-Binding Protein 7

Share to Fatty Acid-Binding Proteins

Share to Inhibition, Psychological

Share to Mice, Inbred Strains

Share to Receptors, N-Methyl-D-Aspartate

Share to Reflex, Startle

Source

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Identifiers

PMID: 18001149
DOI: 10.1371/journal.pbio.0050297
PMCID: PMC2071943

Genes

FABP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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