Article
The HMG-CoA reductase gene and lipid and lipoprotein levels: the multi-ethnic study of atherosclerosis.
Lipids - 1 Aug 2009
Chen Yi-Chun, Chen Yii-Der I, Li Xiaohui, Post Wendy, Herrington David, Polak Joseph F, Rotter Jerome I, Taylor Kent D
Abstract excerpt
HMG-CoA reductase (HMGCR) is an enzyme involved in cholesterol synthesis. To investigate the contribution of the HMGCR gene to lipids and lipoprotein subfractions in different ethnicities, we performed an association study in the Multi-Ethnic Study of Atherosclerosis (MESA). In total, 2,444 MESA subjects [597 African-Americans (AA), 627 Chinese-Americans (CHA), 612 European-Americans (EA), and 608...
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