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Article

Analysis of Plasmodium falciparum var genes expressed in children from Papua New Guinea.

The Journal of infectious diseases - 1 Aug 2009

Falk Nicole, Kaestli Mirjam, Qi Weihong, Ott Michael, Baea Kay, Cortés Alfred, Beck Hans-Peter

Abstract excerpt

BACKGROUND: The variable antigen P. falciparum erythrocyte membrane protein-1 (PfEMP1) is a major virulence factor in malaria. A large number of var genes encode PfEMP1, and we hypothesized that a restricted PfEMP1 repertoire determines clinical disease presentation. We conducted a case-control study in Papua New Guinea and analyzed transcribed var genes in naturally infected children. METHODS: var messenger RNA...

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Identifiers

PMID: 19552523
DOI: 10.1086/600071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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