Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population genomics of the immune evasion (var) genes of Plasmodium falciparum.

PLoS pathogens - 1 Mar 2007

Barry Alyssa E, Leliwa-Sytek Aleksandra, Tavul Livingston, Imrie Heather, Migot-Nabias Florence, Brown Stuart M, McVean Gilean A V, Day Karen P

Abstract excerpt

Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite genome underlies immune evasion. We compared the diversity of the DBLalpha domain of var genes sampled from 30 parasite isolates from a malaria endemic area of Papua New Guinea (PNG) and 59 from widespread geographic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Protozoan
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Genome, Protozoan

Share to Papua New Guinea

Share to Plasmodium falciparum

Share to Protozoan Proteins

Share to Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 17367208
DOI: 10.1371/journal.ppat.0030034
PMCID: PMC1828697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population genomics of the immune evasion (var) genes of Plasmodium falciparum.PMID 17367208Read ↗

Phylogeography of var gene repertoires reveals fine-scale geospatial clustering of Plasmodium falciparum populations in a highly endemic area.Semantic proximity Read ↗

Genetic diversity of the DBLalpha region in Plasmodium falciparum var genes among Asia-Pacific isolates.Semantic proximity Read ↗

Evolutionary analyses of the major variant surface antigen-encoding genes reveal population structure of Plasmodium falciparum within and between continentsSemantic proximity Read ↗

Evolutionary analysis of the most polymorphic gene family in falciparum malariaSemantic proximity Read ↗

A systematic review on genetic diversity of var gene DBL1α domain from different geographical regions in Plasmodium falciparum isolates.Semantic proximity Read ↗

Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates from central Myanmar.Semantic proximity Read ↗

Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.Semantic proximity Read ↗

Sympatric Plasmodium falciparum isolates from Venezuela have structured var gene repertoires.Semantic proximity Read ↗

A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa.Semantic proximity Read ↗

Expressed var gene repertoire and variant surface antigen diversity in a shrinking Plasmodium falciparum population.Semantic proximity Read ↗

Evidence for the importance of genetic structuring to the structural and functional specialization of the <i>Plasmodium falciparum var</i> gene familySemantic proximity Read ↗

Var genes, strain hyperdiversity, and malaria transmission dynamics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.