Article
Diversity and expression of Plasmodium falciparum var gene in severe and mild malaria cases from Central India.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2021
Bhandari Sneha, Krishna Sri, Patel Priyanka P, Singh Mrigendra P, Singh Neeru, Sharma Anjana, Bharti Praveen K
Abstract excerpt
BACKGROUND: Plasmodium falciparum erythrocyte membrane protein is encoded by a highly variable multicopy var gene family known to play a key role in malaria pathogenicity. Therefore, we investigated sequence variation, expression profile and immune response of the Duffy binding-like domain (DBLα) region of the var gene. METHODS: Blood samples were collected from patients with cerebral, severe and mild malaria in...
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