Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The box VII motif of Escherichia coli DnaA protein is required for DnaA oligomerization at the E. coli replication origin.

The Journal of biological chemistry - 3 Dec 2004

Felczak Magdalena M, Kaguni Jon M

Abstract excerpt

Escherichia coli DnaA protein initiates DNA replication from the chromosomal origin, oriC, and regulates the frequency of this process. Structure-function studies indicate that the replication initiator comprises four domains. Based on the structural similarity of Aquifex aeolicus DnaA to other AAA+ proteins that are oligomeric, it was proposed that Domain III functions in oligomerization at oriC (Erzberger, J....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alanine

Share to Amino Acid Motifs

Share to Arginine

Share to DNA Helicases

Share to Hydrolysis

Share to Replication Origin

Source

Identifiers

PMID: 15371441
DOI: 10.1074/jbc.M409695200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The box VII motif of Escherichia coli DnaA protein is required for DnaA oligomerization at the E. coli replication origin.PMID 15371441Read ↗

DnaA Protein of Escherichia coli: oligomerization at the E. coli chromosomal origin is required for initiation and involves specific N-terminal amino acids.Semantic proximity Read ↗

An essential tryptophan of Escherichia coli DnaA protein functions in oligomerization at the E. coli replication origin.Semantic proximity Read ↗

A role for nonessential domain II of initiator protein, DnaA, in replication control.Semantic proximity Read ↗

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin.Semantic proximity Read ↗

A critical DnaA box directs the cooperative binding of the Escherichia coli DnaA protein to the plasmid RK2 replication origin.Semantic proximity Read ↗

A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin.Semantic proximity Read ↗

Mutant DnaA proteins defective in duplex opening of oriC, the origin of chromosomal DNA replication in Escherichia coli.Semantic proximity Read ↗

New non-detrimental DNA-binding mutants of the Escherichia coli initiator protein DnaA.Semantic proximity Read ↗

A nucleotide switch in the Escherichia coli DnaA protein initiates chromosomal replication: evidnece from a mutant DnaA protein defective in regulatory ATP hydrolysis in vitro and in vivo.Semantic proximity Read ↗

The Escherichia coli dnaA gene: four functional domains.Semantic proximity Read ↗

Escherichia coli DnaA protein: specific biochemical defects of mutant DnaAs reduce initiation frequency to suppress a temperature-sensitive dnaX mutation.Semantic proximity Read ↗

Research on DnaA in the early days.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.