Article
Cocaine modulates locomotion behavior in C. elegans.
PloS one - 17 Jun 2009
Ward Alex, Walker Vyvyca J, Feng Zhaoyang, Xu X Z Shawn
Abstract excerpt
Cocaine, a potent addictive substance, is an inhibitor of monoamine transporters, including DAT (dopamine transporter), SERT (serotonin transporter) and NET (norepinephrine transporter). Cocaine administration induces complex behavioral alterations in mammals, but the underlying mechanisms are not well understood. Here, we tested the effect of cocaine on C. elegans behavior. We show for the first time that acute...
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