Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.

BMC neuroscience - 22 Jun 2009

Brown Marishka K, Luo Yuan

Abstract excerpt

BACKGROUND: Dysfunctions in the serotonergic system have been implicated in several neurological disorders such as depression. Elderly individuals who have been diagnosed with clinical depression show elevated cases of neurodegenerative diseases. This has led to suggestions that modulating the serotonin (5-HT) system could provide an alternative method to current therapies for alleviating these pathologies. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloride Channels
Share to Cholinesterase Inhibitors
Share to Cyclopentanes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Furans

Share to Locomotion

Share to Receptors, Serotonin

Share to Serotonin

Share to Serotonin Antagonists

Source

Open in PubMed Open full text

Identifiers

PMID: 19545409
DOI: 10.1186/1471-2202-10-62
PMCID: PMC2714043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.PMID 19545409Read ↗

Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and -independent activities of fluoxetine.Semantic proximity Read ↗

MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans.Semantic proximity Read ↗

The serotonin receptor SER-1 (5HT2ce) contributes to the regulation of locomotion in Caenorhabditis elegans.Semantic proximity Read ↗

Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease.Semantic proximity Read ↗

Neuroprotective potential of Cannabis sativa-based oils in Caenorhabditis elegansSemantic proximity Read ↗

A genetic survey of fluoxetine action on synaptic transmission in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans as a powerful model for neurotoxicity assessmentSemantic proximity Read ↗

Glucose promotes neuron morphology abnormalities and egg-laying defects dependent of the serotonin signaling pathway in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Receptors and other signaling proteins required for serotonin control of locomotion in Caenorhabditis elegans.Semantic proximity Read ↗

MPMT-OX up-regulates GABAergic transmission and protects against seizure-like behavior in Caenorhabditis elegansSemantic proximity Read ↗

Acute blockade of the Caenorhabditis elegans dopamine transporter DAT-1 by the mammalian norepinephrine transporter inhibitor nisoxetine reveals the influence of genetic modifications of dopamine signaling in vivo.Semantic proximity Read ↗

Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.