Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cocaine, reward, movement and monoamine transporters.

Molecular psychiatry - 1 Jan 2002

Uhl G R, Hall F S, Sora I

Abstract excerpt

Recent evidence enriches our understanding of the molecular sites of action of cocaine reward and locomotor stimulation. Dopamine transporter blockade by cocaine appears a sufficient explanation for cocaine-induced locomotion. Variation in DAT appears to cause differences in locomotion without drug stimulation. However, previously-held views that DAT blockade was the sole site for cocaine reward have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cocaine
Share to Cocaine-Related Disorders
Share to Dopamine Plasma Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Neurological

Share to Models, Psychological

Share to Norepinephrine

Share to Norepinephrine Plasma Membrane Transport Proteins

Share to Reward

Source

Identifiers

PMID: 11803442
DOI: 10.1038/sj.mp.4000964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cocaine, reward, movement and monoamine transporters.PMID 11803442Read ↗

Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.Semantic proximity Read ↗

The top 20 dopamine transporter mutants: structure-function relationships and cocaine actions.Semantic proximity Read ↗

Cocaine modulates locomotion behavior in C. elegans.Semantic proximity Read ↗

Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.Semantic proximity Read ↗

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice.Semantic proximity Read ↗

Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism.Semantic proximity Read ↗

Genetics of dopamine and its contribution to cocaine addiction.Semantic proximity Read ↗

Intravenous cocaine induced-activity and behavioural sensitization in norepinephrine-, but not dopamine-transporter knockout mice.Semantic proximity Read ↗

The dopamine transporter: a crucial component regulating dopamine transmission.Semantic proximity Read ↗

Functional mutations in mouse norepinephrine transporter reduce sensitivity to cocaine inhibition.Semantic proximity Read ↗

Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.Semantic proximity Read ↗

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.