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Article

The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 1999

Duerr J S, Frisby D L, Gaskin J, Duke A, Asermely K, Huddleston D, Eiden L E, Rand J B

Abstract excerpt

We have identified the Caenorhabditis elegans homolog of the mammalian vesicular monoamine transporters (VMATs); it is 47% identical to human VMAT1 and 49% identical to human VMAT2. C. elegans VMAT is associated with synaptic vesicles in approximately 25 neurons, including all of the cells reported to contain dopamine and serotonin, plus a few others. When C. elegans VMAT is expressed in mammalian cells, it has...

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PMID: 9870940
PMCID: PMC6782383

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