Article
A mutation of cdc-25.1 causes defects in germ cells but not in somatic tissues in C. elegans.
Molecules and cells - 31 Jul 2009
Kim Jiyoung, Lee Ah-Reum, Kawasaki Ichiro, Strome Susan, Shim Yhong-Hee
Abstract excerpt
By screening C. elegans mutants for severe defects in germline proliferation, we isolated a new loss-of-function allele of cdc-25.1, bn115. bn115 and another previously identified loss-of-function allele nr2036 do not exhibit noticeable cell division defects in the somatic tissues but have reduced numbers of germ cells and are sterile, indicating that cdc-25.1 functions predominantly in the germ line during...
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