Article
C. elegans pro-1 activity is required for soma/germline interactions that influence proliferation and differentiation in the germ line.
Development (Cambridge, England) - 1 Mar 2004
Killian Darrell J, Hubbard E Jane Albert
Abstract excerpt
Strict spatial and temporal regulation of proliferation and differentiation is essential for proper germline development and often involves soma/germline interactions. In C. elegans, a particularly striking outcome of defective regulation of the proliferation/differentiation pattern is the Pro phenotype in which an ectopic mass of proliferating germ cells occupies the proximal adult germ line, a region normally...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation
- Cell Division
- Contractile Proteins
- Genes, Reporter
- Germ Cells
- Gonads
- Meiosis
- Membrane Glycoproteins
- Microfilament Proteins
- Phenotype
- Profilins
- Receptors, Notch
- Recombinant Fusion Proteins
- Sequence Deletion