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Article

CDC-25.1 stability is regulated by distinct domains to restrict cell division during embryogenesis in C. elegans.

Development (Cambridge, England) - 1 Apr 2008

Hebeisen Michaël, Roy Richard

Abstract excerpt

Cdc25 phosphatases are key positive cell cycle regulators that coordinate cell divisions with growth and morphogenesis in many organisms. Intriguingly in C. elegans, two cdc-25.1(gf) mutations induce tissue-specific and temporally restricted hyperplasia in the embryonic intestinal lineage, despite stabilization of the mutant CDC-25.1 protein in every blastomere. We investigated the molecular basis underlying the...

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Identifiers

PMID: 18287204
DOI: 10.1242/dev.014969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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