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MRG-1, a mortality factor-related chromodomain protein, is required maternally for primordial germ cells to initiate mitotic proliferation in C. elegans.

Mechanisms of development - 1 Jun 2002

Fujita Masaki, Takasaki Teruaki, Nakajima Noboru, Kawano Taizo, Shimura Yoshiro, Sakamoto Hiroshi

Abstract excerpt

We identified MRG-1, a Caenorhabditis elegans chromodomain-containing protein that is similar to the human mortality factor-related gene 15 product (MRG15). RNA-mediated interference (RNAi) of mrg-1 resulted in complete absence of the germline in both hermaphrodite and male adults. Examination of...

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PMID: 12175490
DOI: 10.1016/s0925-4773(02)00058-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12175490-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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MRG-1, a mortality factor-related chromodomain protein, is required maternally for primordial germ cells to initiate mitotic proliferation in C. elegans.PMID 12175490Read ↗

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