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Article

Organ-specific cell division abnormalities caused by mutation in a general cell cycle regulator in C. elegans.

Development (Cambridge, England) - 1 May 2002

Kostić Ivana, Roy Richard

Abstract excerpt

The precise control of cell division during development is pivotal for morphogenesis and the correct formation of tissues and organs. One important gene family involved in such control is the p21/p27/p57 class of negative cell cycle regulators. Loss of function of the C. elegans p27 homolog, cki-1, causes extra cell divisions in numerous tissues including the hypodermis, the vulva, and the intestine. We have...

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PMID: 11959825
DOI: 10.1242/dev.129.9.2155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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