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Article

Mutant alpha-synuclein overexpression mediates early proinflammatory activity.

Neurotoxicity research - 1 Oct 2009

Su Xiaomin, Federoff Howard J, Maguire-Zeiss Kathleen A

Abstract excerpt

Microglia provide immune surveillance for the brain through both the removal of cellular debris and protection against infection by microorganisms and "foreign" molecules. Upon activation, microglia display an altered morphology and increased expression of proinflammatory molecules. Increased numbers of activated microglia have been identified in a number of neurodegenerative diseases including Parkinson's...

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Identifiers

PMID: 19526281
DOI: 10.1007/s12640-009-9053-x
PMCID: PMC2877375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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