Article
Glucokinase regulatory protein gene polymorphism affects postprandial lipemic response in a dietary intervention study.
Human genetics - 1 Oct 2009
Shen Haiqing, Pollin Toni I, Damcott Coleen M, McLenithan John C, Mitchell Braxton D, Shuldiner Alan R
Abstract excerpt
Postprandial triglyceridemia is an emerging risk factor for cardiovascular disease. However, most of the genes that influence postprandial triglyceridemia are not known. We evaluated whether a common nonsynonymous SNP rs1260326/P446L in the glucokinase regulatory protein (GCKR) gene influenced variation in the postprandial lipid response after a high-fat challenge in seven hundred and seventy participants in the...
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