Article
GCKR variants increase triglycerides while protecting from insulin resistance in Chinese children.
PloS one - 1 Jan 2013
Shen Yue, Wu Lijun, Xi Bo, Liu Xin, Zhao Xiaoyuan, Cheng Hong, Hou Dongqing, Wang Xingyu, Mi Jie
Abstract excerpt
BACKGROUND: Variants in gene encoding glucokinase regulator protein (GCKR) were found to have converse effects on triglycerides and glucose metabolic traits. We aimed to investigate the influence of GCKR variants for triglycerides and glucose metabolic traits in Chinese children and adults. METHODS AND RESULTS: We genotyped two GCKR variants rs1260326 and rs1260333 in children and adults, and analyzed the...
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