The n-3 long-chain PUFAs modulate the impact of the GCKR Pro446Leu polymorphism on triglycerides in adolescents.

doi:10.1194/jlr.M057570

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Article

The n-3 long-chain PUFAs modulate the impact of the GCKR Pro446Leu polymorphism on triglycerides in adolescents.

Journal of lipid research - 1 Sept 2015

Rousseaux Julien, Duhamel Alain, Dumont Julie, Dallongeville Jean, Molnar Denes, Widhalm Kurt, Manios Yannis, Sjöström Michael, Kafatos Anthony, Breidenassel Christina, Gonzales-Gross Marcela, Cuenca-Garcia Magdalena, Censi Laura, Ascensión Marcos, De Henauw Stefaan, Moreno Luis A, Meirhaeghe Aline, Gottrand Frédéric

Abstract excerpt

Dietary n-3 long-chain PUFAs (LC-PUFAs) are associated with improvement in the parameters of the metabolic syndrome (MetS). Glucokinase regulatory protein (GCKR) is a key protein regulating intracellular glucose disposal. Our aim was to investigate: i) the relationship between the GCKR rs1260326 (Pro446Leu) polymorphism and parameters of the MetS; and ii) a potential influence of n-3 and n-6 LC-PUFA levels on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing

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PMID: 26136510
DOI: 10.1194/jlr.M057570
PMCID: PMC4548781

Genes

GCKR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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