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Article

Transport of nucleoside analogs across the plasma membrane: a clue to understanding drug-induced cytotoxicity.

Current drug metabolism - 1 May 2009

Huber-Ruano I, Pastor-Anglada M

Abstract excerpt

Nucleoside analogs are widely used in the treatment of cancer and viral-induced diseases. Efficacy of treatments relies upon a variety of events, including transport across tissue and target barriers, which determine drug pharmacokinetics and target cell bioavailability. To exert their action, nucleosides have to be chemically modified, thus compromising cellular uptake by those routes which are responsible for...

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PMID: 19519343
DOI: 10.2174/138920009788499030

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OAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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