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Article

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

2019-08-08

Abstract excerpt

The activity and potency of a drug is inherently affected by the metabolic state of its target cell. Solute Carriers (SLCs) represent the largest family of transmembrane transporters in humans and constitute major determinants of cellular metabolism. Several SLCs have been shown to be required for the uptake of individual chemical compounds into cellular systems, but systematic surveys of transporter-drug relation...

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Identifiers and source

Literature Corpus work
85229173-64b5-50ee-94e4-5c05fe202fb4
DOI
10.1101/726539
Open publication

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A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugsDOI 10.1101/726539
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