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Article

In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy.

Handbook of experimental pharmacology - 1 Jan 2011

Burckhardt Gerhard, Burckhardt Birgitta Christina

Abstract excerpt

Organic anion transporters 1-10 (OAT1-10) and the urate transporter 1 (URAT1) belong to the SLC22A gene family and accept a huge variety of chemically unrelated endogenous and exogenous organic anions including many frequently described drugs. OAT1 and OAT3 are located in the basolateral membrane of renal proximal tubule cells and are responsible for drug uptake from the blood into the cells. OAT4 in the apical...

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Source

Identifiers

PMID: 21103968
DOI: 10.1007/978-3-642-14541-4_2

Genes

OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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