Article
The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29.
Molecular aspects of medicine - 1 Jan 2000
Young James D, Yao Sylvia Y M, Baldwin Jocelyn M, Cass Carol E, Baldwin Stephen A
Abstract excerpt
Nucleoside transport in humans is mediated by members of two unrelated protein families, the SLC28 family of cation-linked concentrative nucleoside transporters (CNTs) and the SLC29 family of energy-independent, equilibrative nucleoside transporters (ENTs). These families contain three and four members, respectively, which differ both in the stoichiometry of cation coupling and in permeant selectivity. Together,...
Topics
- Adenosine
- Brain
- Cations
- Equilibrative Nucleoside Transport Proteins
- Humans
- Intestinal Mucosa
- Kidney
- Liver
- Membrane Transport Proteins
- Models, Biological
- Models, Molecular
- Molecular Structure
- Multigene Family
- Phylogeny
- Polymorphism, Single Nucleotide
- Protein Conformation
- Species Specificity