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Article

Equilibrative nucleoside transporters-A review.

Nucleosides, nucleotides & nucleic acids - 2 Jan 2017

Boswell-Casteel Rebba C, Hays Franklin A

Abstract excerpt

Equilibrative nucleoside transporters (ENTs) are polytopic integral membrane proteins that mediate the transport of nucleosides, nucleobases, and therapeutic analogs. The best-characterized ENTs are the human transporters hENT1 and hENT2. However, non-mammalian eukaryotic ENTs have also been studied (e.g., yeast, parasitic protozoa). ENTs are major pharmaceutical targets responsible for modulating the efficacy of...

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Identifiers

PMID: 27759477
DOI: 10.1080/15257770.2016.1210805
PMCID: PMC5728162

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