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Article

Drug Transporter Pharmacogenetics in Nucleoside-Based Therapies

27 May 2010

Abstract excerpt

This article focuses on the different types of transporter proteins that have been implicated in the influx and efflux of nucleoside-derived drugs currently used in the treatment of cancer, viral infections (i.e., AIDS) and other conditions, including autoimmune and inflammatory diseases. Genetic variations in nucleoside-derived drug transporter proteins encoded by the gene families SLC15, SLC22, SLC28, SLC29,...

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PMID: 20504255
DOI: 10.2217/pgs.10.70

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