Article
Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillin.
PLoS biology - 12 May 2009
Shan Yongli, Yu Lihou, Li Yan, Pan Youdong, Zhang Qiangge, Wang Fubin, Chen Jianfeng, Zhu Xueliang
Abstract excerpt
Adhesion and detachment are coordinated critical steps during cell migration. Conceptually, efficient migration requires both effective stabilization of membrane protrusions at the leading edge via nascent adhesions and their successful persistence during retraction of the trailing side via disruption of focal adhesions. As nascent adhesions are much smaller in size than focal adhesions, they are expected to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
