Article
Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion.
The Journal of cell biology - 25 Dec 2000
Nikolopoulos S N, Turner C E
Abstract excerpt
Paxillin is a focal adhesion adapter protein involved in the integration of growth factor- and adhesion-mediated signal transduction pathways. Paxillin LD motifs have been demonstrated to bind to several proteins associated with remodeling of the actin cytoskeleton including the focal adhesion kinase, vinculin, and a complex of proteins comprising p95PKL, PIX, and PAK (Turner, C.E., M. C. Brown, J.A. Perrotta,...
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