Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ezrin Phosphorylation at T567 Modulates Cell Migration, Mechanical Properties, and Cytoskeletal Organization.

International journal of molecular sciences - 9 Jan 2020

Zhang Xiaoli, Flores Luis R, Keeling Michael C, Sliogeryte Kristina, Gavara Núria

Abstract excerpt

Ezrin, a member of the ERM (ezrin/radixin/moesin) family of proteins, serves as a crosslinker between the plasma membrane and the actin cytoskeleton. By doing so, it provides structural links to strengthen the connection between the cell cortex and the plasma membrane, acting also as a signal transducer in multiple pathways during migration, proliferation, and endocytosis. In this study, we investigated the role...

Topics

Join the communities discussing this publication.

Actin Cytoskeleton
Biomechanical Phenomena
Cytoskeletal Proteins
Cytoskeleton
NIH 3T3 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphothreonine

Source

Open in PubMed Open full text

Identifiers

PMID: 31936668
DOI: 10.3390/ijms21020435
PMCID: PMC7013973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ezrin Phosphorylation at T567 Modulates Cell Migration, Mechanical Properties, and Cytoskeletal Organization.PMID 31936668Read ↗

Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migrationSemantic proximity Read ↗

Ezrin Mediates Invasion and Metastasis in Tumorigenesis: A ReviewSemantic proximity Read ↗

Epithelial density controls cell migration through an adhesion-nucleus mechanotransduction pathwaySemantic proximity Read ↗

Pathophysiological Roles of Actin-Binding Scaffold Protein, EzrinSemantic proximity Read ↗

Ezrin Ser66 phosphorylation regulates invasion and metastasis of esophageal squamous cell carcinoma cells by mediating filopodia formation.Semantic proximity Read ↗

Alterations of Cytoskeleton Networks in Cell Fate Determination and Cancer DevelopmentSemantic proximity Read ↗

Modulation of membrane–cytoskeleton interactions: ezrin as key playerSemantic proximity Read ↗

Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad.Semantic proximity Read ↗

Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42.Semantic proximity Read ↗

Identification of a 55-kDa ezrin-related protein that induces cytoskeletal changes and localizes to the nucleolus.Semantic proximity Read ↗

Stress-activated MAPKs and CRM1 regulate the subcellular localization of Net1A to control cell motility and invasion.Semantic proximity Read ↗

The Janus-faced role of ezrin in "linking" cells to either normal or metastatic phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.