Article
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration.
Scientific reports - 1 Jan 2012
Khatau Shyam B, Bloom Ryan J, Bajpai Saumendra, Razafsky David, Zang Shu, Giri Anjil, Wu Pei-Hsun, Marchand Jorge, Celedon Alfredo, Hale Christopher M, Sun Sean X, Hodzic Didier, Wirtz Denis
Abstract excerpt
Cells often migrate in vivo in an extracellular matrix that is intrinsically three-dimensional (3D) and the role of actin filament architecture in 3D cell migration is less well understood. Here we show that, while recently identified linkers of nucleoskeleton to cytoskeleton (LINC) complexes pla...
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