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Article

Association of ATG16L1 gene haplotype with inflammatory bowel disease in Indians.

PloS one - 1 Jan 2017

Pugazhendhi Srinivasan, Baskaran Kirankumar, Santhanam Srikanth, Ramakrishna Balakrishnan S

Abstract excerpt

Inflammatory bowel disease (IBD) is characterized by multigenic inheritance. Defects in autophagy related genes are considered to show genetic heterogeneity between populations. We evaluated the association of several single nucleotide polymorphisms (SNPs) in the autophagy related 16 like 1 (ATG16L1) gene with IBD in Indians. The ATG16L1 gene was genotyped for ten different SNPs using DNA extracted from...

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PMID: 28542425
DOI: 10.1371/journal.pone.0178291
PMCID: PMC5438258

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