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Article

Integration-deficient lentiviral vectors: a slow coming of age.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Aug 2009

Wanisch Klaus, Yáñez-Muñoz Rafael J

Abstract excerpt

Lentiviral vectors are very efficient at transducing dividing and quiescent cells, which makes them highly useful tools for genetic analysis and gene therapy. Traditionally this efficiency was considered dependent on provirus integration in the host cell genome; however, recent results have challenged this view. So called integration-deficient lentiviral vectors (IDLVs) can be produced through the use of...

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Identifiers

PMID: 19491821
DOI: 10.1038/mt.2009.122
PMCID: PMC2835240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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