Article
HIV-1 vectors: fulfillment of expectations, further advancements, and still a way to go.
Current HIV research - 1 Oct 2003
Cockrell Adam S, Kafri Tal
Abstract excerpt
The ability of lentiviral vectors to transduce and stably integrate their genomes into non-dividing cells was the major reason for the development of the HIV-1 based vector gene delivery system. The first VSV-G pseudotyped lentiviral vectors fulfilled these expectations by ferrying large genetic payloads to non-dividing cells in vitro and in vivo. Here we discuss advances in HIV-1 vector systems which lead to...
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