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Clinical use of lentiviral vectors

22 Mar 2018

Abstract excerpt

Viral vectors provide an efficient means for modification of eukaryotic cells, and their use is now commonplace in academic laboratories and industry for both research and clinical gene therapy applications. Lentiviral vectors, derived from the human immunodeficiency virus, have been extensively investigated and optimized over the past two decades. Third-generation, self-inactivating lentiviral vectors have...

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PMID: 29654266
DOI: 10.1038/s41375-018-0106-0

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