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Purification and characterization of Caenorhabditis elegans NTH, a homolog of human endonuclease III: essential role of N-terminal region.

DNA repair - 4 Jul 2009

Morinaga Hironobu, Yonekura Shin-Ichiro, Nakamura Nobuya, Sugiyama Hiroshi, Yonei Shuji, Zhang-Akiyama Qiu-Mei

Abstract excerpt

Oxidatively damaged bases in DNA cause many types of deleterious effects. The main enzyme that removes such lesions is DNA glycosylase, and accordingly, DNA glycosylase plays an important role in genome stability. Recently, a relationship between DNA glycosylases and aging has been suggested, but it remains controversial. Here, we investigated DNA glycosylases of C. elegans, which is a useful model organism for...

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PMID: 19481506
DOI: 10.1016/j.dnarep.2009.04.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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