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Article

Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Hazra Tapas K, Izumi Tadahide, Boldogh Istvan, Imhoff Barry, Kow Yoke W, Jaruga Pawel, Dizdaroglu Miral, Mitra Sankar

Abstract excerpt

8-oxoguanine (8-oxoG), ring-opened purines (formamidopyrimidines or Fapys), and other oxidized DNA base lesions generated by reactive oxygen species are often mutagenic and toxic, and have been implicated in the etiology of many diseases, including cancer, and in aging. Repair of these lesions in...

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Identifiers

PMID: 11904416
DOI: 10.1073/pnas.062053799
PMCID: PMC122556

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11904416-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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