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Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents.

DNA repair - 5 Aug 2010

Skjeldam Hanne K, Kassahun Henok, Fensgård Oyvind, SenGupta Tanima, Babaie Eshrat, Lindvall Jessica M, Arczewska Katarzyna, Nilsen Hilde

Abstract excerpt

The nematode Caenorhabditis elegans has been used extensively to study responses to DNA damage. In contrast, little is known about DNA repair in this organism. C. elegans is unusual in that it encodes few DNA glycosylases and the uracil-DNA glycosylase (UDG) encoded by the ung-1 gene is the only known UDG. C. elegans could therefore become a valuable model organism for studies of the genetic interaction networks...

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PMID: 20493785
DOI: 10.1016/j.dnarep.2010.04.009

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UNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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