Article
Butyrylcholinesterase, ApoE and Alzheimer's disease in a population from the Canary Islands (Spain).
Neuroscience letters - 29 Oct 2007
Déniz-Naranjo Maria Cándida, Muñoz-Fernández Carmen, Alemany-Rodríguez Maria Jesús, del Carmen Pérez-Vieitez Maria, Aladro-Benito Yolanda, Irurita-Latasa Juncal, Sánchez-García Florentino
Abstract excerpt
AIM: Cholinergic dysfunction is a major neurochemical feature in Alzheimer's disease (AD), accountable for many cognitive dysfunctions and some psychiatric symptoms. Butyrylcholinesterase (BChE) is one of the cholinesterases with increased activity in the brain of Alzheimer's patients. Several mutations code for different BChE, such as the K variant, which is the most common and is capable of reducing BChE...
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