Article
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Feb 1994
Morrison A, Sugino A
Abstract excerpt
DNA polymerases II (epsilon) and III (delta) are the only nuclear DNA polymerases known to possess an intrinsic 3'-->5' exonuclease in Saccharomyces cerevisiae. We have investigated the spontaneous mutator phenotypes of DNA polymerase delta and epsilon 3'-->5' exonuclease-deficient mutants, pol3-...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA Polymerase II
- DNA Polymerase III
- DNA Repair
- DNA Replication
- DNA, Fungal
- DNA-Directed DNA Polymerase
- Haploidy
- Humans
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae