Genetics of hypertension: from experimental models to clinical applications.

Abstract excerpt

Human essential hypertension is a complex, multifactorial, quantitative trait under a polygenic control. Over the last decade several strategies have been used to dissect the genetic determinants of hypertension. Of these strategies, the study of rare monogenic forms of hypertension has been the most successful. Attempts to identify the multiple genes involved in the more common polygenic form of hypertension has...

Topics

• Animals
• Blood Pressure
• Disease Models, Animal
• Gene Expression
• Genetic Linkage
• Genetic Predisposition to Disease
• Humans
• Hypertension
• Phenotype